Eight CAR-T companies tackling autoimmune disorders
The article reviews CAR-T companies developing therapies for autoimmune diseases. Kyverna Therapeutics’ miv-cel (CD19) is in phase 3 for stiff person syndrome, with a rolling FDA BLA filing started in May and completion expected by year end. Cabaletta’s rese-cel (CD19) is in phase 1/2 for SLE and other indications, with June myositis results. Cartesian’s Descartes-08 (BCMA, mRNA) is in phase 3 for myasthenia gravis.



