$CELZ

CREATIVE MEDICAL TECHNOLOGY HOLDINGS, INC.

Creative Medical Technology Holdings is a commercial-stage biotechnology company developing regenerative therapies in immunotherapy, endocrinology, urology, neurology and orthopedics. Its programs include AlloStem, an allogenic cell therapy platform; ImmCelz, which uses a patient’s reprogrammed immune cells; and iPScelz, an induced pluripotent stem cell program. Other products and procedures include CELZ-201 therapies for Type 1 diabetes and lower back pain, StemSpine for chronic lower back pain, OvaStem for premature ovarian failure, and CaverStem and FemCelz for sexual health conditions. The company also develops cell therapies for additional indications and offers procedures using patients’ own cells. The company makes money from sales of products and procedures and may receive payments from licensing intellectual property; CaverStem generated minimal revenues in 2023 and 2024. Its principal executive offices are in Phoenix, Arizona.

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Average knee pain scores fell about 65% over six months in a 30-person study

Creative Medical Technology Holdings (CELZ) presented clinical and lab findings for Ultrasome™, its cell-free regenerative medicine platform. A 30-patient study showed 65% reduction in average pain score and 52% reduction in WOMAC score over six months. No serious adverse events were reported. The company plans to publish full findings in a peer-reviewed manuscript.

Timothy Warbington Discloses Investment at Creative Medical Technology with 13.7% Stake

Timothy Warbington, CEO of Creative Medical Technology Holdings (CELZ), disclosed a 13.7% stake in the company's common stock. The investment follows a deal where Creative Acquisition Corp., led by Warbington, received 1 million restricted shares. Warbington plans to hold the shares for investment purposes but may buy or sell more in the future. He has no current plans for board changes or mergers. Warbington also serves as Chairman and CEO of Creative Acquisition Corp.

CREATIVE MEDICAL TECHNOLOGY HOLDINGS, INC. (CELZ): Entry into a Material Definitive Agreement

CREATIVE MEDICAL TECHNOLOGY HOLDINGS, INC. (CELZ) filed an SEC Form 8-K — Entry into a Material Definitive Agreement. Item 1.01 Entry into a Material Definitive Agreement. On September 24, 2026, Creative Medical Technology Holdings, Inc. (the “Company”) entered into a Stock Purchase Agreement (the “Purchase Agreement”) with Creative Acquisition Corp. (“CAC”), pursuant to which the Company purcha

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Timothy Warbington Discloses Investment at Creative Medical Technology with 13.7% Stake

Timothy Warbington, CEO of Creative Medical Technology Holdings (CELZ), disclosed a 13.7% stake in the company's common stock. The investment follows a deal where Creative Acquisition Corp., led by Warbington, received 1 million restricted shares. Warbington plans to hold the shares for investment purposes but may buy or sell more in the future. He has no current plans for board changes or mergers. Warbington also serves as Chairman and CEO of Creative Acquisition Corp.

CREATIVE MEDICAL TECHNOLOGY HOLDINGS, INC. (CELZ): Entry into a Material Definitive Agreement

CREATIVE MEDICAL TECHNOLOGY HOLDINGS, INC. (CELZ) filed an SEC Form 8-K — Entry into a Material Definitive Agreement. Item 1.01 Entry into a Material Definitive Agreement. On September 24, 2026, Creative Medical Technology Holdings, Inc. (the “Company”) entered into a Stock Purchase Agreement (the “Purchase Agreement”) with Creative Acquisition Corp. (“CAC”), pursuant to which the Company purcha

CREATIVE MEDICAL TECHNOLOGY HOLDINGS, INC. (CELZ): Submission of Matters to a Vote of Security Holders

CREATIVE MEDICAL TECHNOLOGY HOLDINGS, INC. (CELZ) filed an SEC Form 8-K — Submission of Matters to a Vote of Security Holders. Item 5.03 Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year. On August 28, 2026, the stockholders of Creative Medical Technology Holdings, Inc. (the “Company”) approved an amendment to the Company’s Articles of Incorporation to increase the number of author

CREATIVE MEDICAL TECHNOLOGY HOLDINGS, INC. (CELZ): Entry into a Material Definitive Agreement

CREATIVE MEDICAL TECHNOLOGY HOLDINGS, INC. (CELZ) filed an SEC Form 8-K — Entry into a Material Definitive Agreement. EX-4.1 2 celz_ex41.htm FORM OF INDUCEMENT WARRANT celz_ex41.htm EXHIBIT 4.1 NEITHER THIS SECURITY NOR THE SECURITIES FOR WHICH THIS SECURITY IS EXERCISABLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON

Creative Medical Technology Holdings Issues Mid-Year Update

Creative Medical Technology Holdings (NASDAQ: CELZ) issued a mid-year update. It said Olastrocel (CELZ-201) has WHO-approved naming and reported positive interim 180-day ADAPT trial results; the FDA cleared an expanded cohort for patients using <90 mg/day morphine equivalents. Ultrasome™ pilot data showed a 93% primary endpoint response. The CELZ-Biodefense Atlas program advanced to nationwide AI-enabled veteran data collection.

Creative Medical Technology Holdings Announces Agreements for Exercise of Warrants for $4.5 Million Gross Proceeds

Creative Medical Technology Holdings (Nasdaq: CELZ) said it agreed with warrant holders to immediately exercise existing warrants for up to 2,790,340 shares at a reduced $1.60 exercise price, raising about $4.5M gross proceeds before fees. In return, it will issue new unregistered warrants for up to 5,580,680 shares at $1.60, pending shareholder approval. Closing expected June 30, 2026.

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Creative Medical Technology Expands ADAPT Trial After New FDA Clearance

Creative Medical Technology (CELZ) said the FDA cleared an amended protocol to expand its ADAPT trial of Olastrocel (CELZ-201) for chronic lower back pain. The company will add 15 patients using <90 mg morphine equivalents/day; the new cohort is 85% enrolled and uses its AI pain-medication monitoring. Creative Medical cited positive 180-day interim results and a DSMB report of no significant adverse events, and said it is preparing for Phase 3 discussions.

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