Kazia Therapeutics Expands Ongoing Phase 1b Trial of Paxalisib in Advanced Breast Cancer
Kazia Therapeutics (NASDAQ: KZIA) said it will expand its ongoing Phase 1b trial of paxalisib plus standard-of-care therapy in advanced triple-negative breast cancer. The company plans to increase enrollment from 12 to 36 patients, citing continued safety, tolerability and early clinical activity. It aims to further assess dose optimization and preliminary efficacy with pembrolizumab and chemotherapy, and expects updates through 2026–2027.