$MLYS

Mineralys Therapeutics, Inc.

1
1
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$5.1M
Warren Eric
67%
See all $MLYS insider activity →

H.C. Wainwright reiterates Mineralys stock rating on new data

H.C. Wainwright reiterated a Buy rating and $56.00 price target for Mineralys Therapeutics (NASDAQ:MLYS), citing new clinical data for lorundrostat. The target implies 140% upside from the current stock price of $23.37. The firm highlights the drug's potential in treating difficult-to-treat hypertension ahead of a December 2026 PDUFA date. Mineralys reported a wider-than-expected Q2 2026 loss of $2.85 per share. UBS initiated coverage with a Neutral rating and $29.00 price target.

Mineralys Therapeutics Presents New Data for Lorundrostat at the American Heart Association Hypertension Scientific Sessions 2026

Mineralys Therapeutics (MLYS) presented data at the American Heart Association Hypertension Scientific Sessions 2026. In the Launch-HTN trial, 46% of participants with difficult-to-treat hypertension achieved the AHA/ACC systolic blood pressure target of <130 mmHg with lorundrostat 50 mg. In the Explore-OSA trial, lorundrostat reduced morning systolic blood pressure by 11.1 mmHg at Week 4. Both trials showed favorable safety and tolerability profiles for lorundrostat.

MLYS sentiment & insider activity

Over the past 7 days, AlphAI's AI scored 2 news stories mentioning MLYS (Mineralys Therapeutics, Inc.). Coverage has skewed bullish: 1 bullish, 1 neutral, and 0 bearish.

Recent MLYS coverage spans financial news, insider activity and technology.

In the last 30 days, MLYS insiders filed 3 SEC Form 4 transactions — no purchases and 3 sales ($5.1M). The most active reporter was Warren Eric, Chief Commercial Officer, with 1 filing. 67% of those filings were made under pre-arranged Rule 10b5-1 plans.

What's driving MLYS

  • UBS initiated coverage on Mineralys Therapeutics with a neutral rating and a $29 price target. The company's stock is currently trading at $23.37, with a 5-day increase of 4.42% and a year-to-date decrease of 1.10%. Mineralys reported a widened Q2 2026 loss, according to the company.

    marketscreener.com · Oct 12, 2026

  • Analyst upgrade with a higher target suggests upside potential.

    investing.com · Oct 12, 2026

  • Positive pivotal trial results likely boost investor confidence and may drive short-term price appreciation.

    globenewswire.com · Oct 9, 2026

  • Insider sale may signal reduced confidence and could pressure the stock lower.

    SEC EDGAR · Oct 2, 2026

  • The upcoming presentation could move the stock if data are positive, but no results are disclosed yet.

    globenewswire.com · Oct 2, 2026

AlphAI scores every news story that mentions MLYS with an AI model for sentiment and relevance, and aggregates insider trades from Mineralys Therapeutics, Inc.'s SEC EDGAR Form 4 filings. Figures refresh continuously.

News on $MLYS

Score
$MLYSHigh

H.C. Wainwright reiterates Mineralys stock rating on new data

H.C. Wainwright reiterated a Buy rating and $56.00 price target for Mineralys Therapeutics (NASDAQ:MLYS), citing new clinical data for lorundrostat. The target implies 140% upside from the current stock price of $23.37. The firm highlights the drug's potential in treating difficult-to-treat hypertension ahead of a December 2026 PDUFA date. Mineralys reported a wider-than-expected Q2 2026 loss of $2.85 per share. UBS initiated coverage with a Neutral rating and $29.00 price target.

$MLYSHighAI 9/10

Mineralys Therapeutics Presents New Data for Lorundrostat at the American Heart Association Hypertension Scientific Sessions 2026

Mineralys Therapeutics (MLYS) presented data at the American Heart Association Hypertension Scientific Sessions 2026. In the Launch-HTN trial, 46% of participants with difficult-to-treat hypertension achieved the AHA/ACC systolic blood pressure target of <130 mmHg with lorundrostat 50 mg. In the Explore-OSA trial, lorundrostat reduced morning systolic blood pressure by 11.1 mmHg at Week 4. Both trials showed favorable safety and tolerability profiles for lorundrostat.

Mineralys Therapeutics Announces Presentation of New Lorundrostat Data at the American Society of Nephrology (ASN) Kidney Week 2026

Mineralys Therapeutics (MLYS) will present new data from its Launch-HTN trial of lorundrostat at the American Society of Nephrology Kidney Week 2026. The trial, involving patients with uncontrolled hypertension, showed lorundrostat's potential in reducing blood pressure and albuminuria in chronic kidney disease stages 1-3. The company aims to address hypertension and related comorbidities driven by dysregulated aldosterone.

$MLYSMed

Mineralys Therapeutics Soars After Bold Royalty Deal - TipRanks.com

Mineralys Therapeutics (MLYS) shares rose after the company acquired future royalty obligations for its lead drug, lorundrostat, potentially increasing long-term profits if approved. Analysts initiated coverage with undervalued ratings, and institutional buying was reported ahead of the FDA's 2026 decision. The stock has fallen 30.37% YTD, with a market cap of $2.27B. Risks include clinical setbacks and financial strain due to cash burn and debt.

$MLYSMed

Why Mineralys Therapeutics (MLYS) Is Getting Fresh Attention

Mineralys Therapeutics (MLYS) reported a Q2 2026 net loss of $241.07M. The company appointed James J. Ferguson III, M.D., as Chief Medical Officer. Shares are down 5.04% in 30 days and 14.07% in 90 days, but up 72.32% in 1 year and 97.31% in 3 years. Analysts suggest fair value at $50.88, above the current $25.65, based on lorundrostat's potential. Risks include regulatory outcomes and cash burn.

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