$NRIX

Nurix Therapeutics, Inc.

Nurix Therapeutics is a clinical-stage biopharmaceutical company that discovers and develops targeted protein degradation medicines for patients with cancer and inflammatory diseases. Its wholly owned clinical pipeline includes bexobrutideg, a BTK degrader; zelebrudomide, which degrades BTK and the transcription factors Ikaros and Aiolos; and NX-1607, a CBL-B inhibitor. Nurix also advances preclinical protein degraders and degrader antibody conjugates for oncology, inflammation and immunology. Nurix uses its DEL-AI discovery platform, which applies machine learning to drug discovery, across its wholly owned and partnered pipelines. Collaborations with Gilead Sciences, Sanofi and Pfizer include drug discovery programs and can provide fees, milestone payments and royalties on future product sales. Nurix retains certain U.S. co-development, co-commercialization and profit-sharing options for multiple candidates. Nurix is headquartered in Brisbane, California.

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$1.4M
Ring Christine
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Nurix Therapeutics stock is up, what you need to know

Nurix Therapeutics (NRIX) shares rose 3.4% after appointing Dr. Arati V. Rao as chief medical officer. Dr. Rao will oversee clinical development, including the BTK degrader bexobrutideg partnered with Roche. The stock closed at $16.33, up 2.8% from the previous close. Nurix has faced volatility, including a 39.8% drop last week due to Sanofi ending a Phase 1 study. The company has $1.1B in cash, funding operations into 2029.

Sanofi’s decision to stop SAR448272 development impacts Nurix

Nurix Therapeutics (NRIX) shares dropped 38% in after-hours trading on Tuesday after Sanofi (SAN) decided to halt the Phase I trial of SAR448272, an oral STAT6 degrader. Sanofi notified Nurix of the decision to discontinue the clinical trial.

Cathie Wood Sells $12.8 Million Of Alphabet, Days After The Stock Suffered Its Worst Day Since Its 2004 IPO, Losing Nearly Half A Trillion Dollars In Market Value

ARK Invest sold $12.8 million in Alphabet shares on Nov. 4 and $3.5 million on Nov. 3, following Alphabet's worst day as a public company. Alphabet's Q3 revenue missed estimates, with search revenue below expectations. ARK also sold shares in Eli Lilly and Amazon, and bought Nurix Therapeutics. Alphabet's stock is down 12.81% since its Oct. 28 close.

NRIX sentiment & insider activity

Over the past 7 days, AlphAI's AI scored 4 news stories mentioning NRIX (Nurix Therapeutics, Inc.). Coverage has been balanced: 1 bullish, 2 neutral, and 1 bearish.

Recent NRIX coverage spans financial news and insider activity.

In the last 30 days, NRIX insiders filed 11 SEC Form 4 transactions — no purchases and 11 sales ($1.4M). The most active reporter was Ring Christine, Chief Legal Officer, with 4 filings. 73% of those filings were made under pre-arranged Rule 10b5-1 plans.

What's driving NRIX

  • Nurix Therapeutics (NRIX) shares rose 3.4% after appointing Dr. Arati V. Rao as chief medical officer. Dr. Rao will oversee clinical development, including the BTK degrader bexobrutideg partnered with Roche. The stock closed at $16.33, up 2.8% from the previous close. Nurix has faced volatility, including a 39.8% drop last week due to Sanofi ending a Phase 1 study. The company has $1.1B in cash, funding operations into 2029.

    tradingview.com · Nov 11, 2026

  • Significant negative pressure on NRIX as the lead program is discontinued.

    thepharmaletter.com · Nov 6, 2026

  • Potential upside if the Phase 3 DAYBreak trial progresses, but short‑term volatility likely.

    247wallst.com · Nov 6, 2026

  • Positive early‑stage data could lift the stock as investors reassess the drug's potential.

    investing.com · Nov 5, 2026

  • Potential upside as ARK adds position.

    investing.com · Nov 5, 2026

AlphAI scores every news story that mentions NRIX with an AI model for sentiment and relevance, and aggregates insider trades from Nurix Therapeutics, Inc.'s SEC EDGAR Form 4 filings. Figures refresh continuously.

News on $NRIX

Score

Nurix Therapeutics stock is up, what you need to know

Nurix Therapeutics (NRIX) shares rose 3.4% after appointing Dr. Arati V. Rao as chief medical officer. Dr. Rao will oversee clinical development, including the BTK degrader bexobrutideg partnered with Roche. The stock closed at $16.33, up 2.8% from the previous close. Nurix has faced volatility, including a 39.8% drop last week due to Sanofi ending a Phase 1 study. The company has $1.1B in cash, funding operations into 2029.

Cathie Wood Sells $12.8 Million Of Alphabet, Days After The Stock Suffered Its Worst Day Since Its 2004 IPO, Losing Nearly Half A Trillion Dollars In Market Value

ARK Invest sold $12.8 million in Alphabet shares on Nov. 4 and $3.5 million on Nov. 3, following Alphabet's worst day as a public company. Alphabet's Q3 revenue missed estimates, with search revenue below expectations. ARK also sold shares in Eli Lilly and Amazon, and bought Nurix Therapeutics. Alphabet's stock is down 12.81% since its Oct. 28 close.

$NRIXMedAI 8/10

Nurix to present bexobrutideg data at ASH meeting

Nurix Therapeutics (NASDAQ:NRIX) will present Phase 1a/1b study data for bexobrutideg at the ASH meeting in December 2026. The data shows clinical activity and tolerability at 600 mg daily. The drug is being developed with Roche for treating relapsed/refractory CLL and SLL. Nurix is also conducting multiple clinical trials, including Phase 2 and 3 studies.

$NRIXMedAI 8/10

Sanofi Discontinues Nurix Therapeutics STAT6 Degrader Program

Sanofi ended a Phase 1 trial of STAT6 degrader SAR448272 and terminated the program, per a Nov. 3, 2026, notice to Nurix Therapeutics. Nurix remains eligible for milestone payments and royalties from other licensed programs under the Sanofi collaboration. Analysts have a Buy rating and $35.00 price target for NRIX, while Spark's AI Analyst rates it Neutral.

$NRIXHighAI 8/10

Nurix Therapeutics, Inc. announced that collaboration partner Sanofi S.A. had notified the Company of its decision to discontinue the Phase 1 first-in-human…

Nurix Therapeutics, Inc. (NRIX) filed an SEC Form 8-K — Other Events. Item 8.01 Other Events. On November 3, 2026, Nurix Therapeutics, Inc. (the “ Company ”) announced that collaboration partner Sanofi S.A. (“ Sanofi ”) had notified the Company of its decision to discontinue the Phase 1 first-in-human clinical trial of SAR448272, an oral STAT6 degr

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