$PRTA

PROTHENA CORP PUBLIC LTD CO

Prothena is an Irish biotechnology company developing therapies for diseases associated with protein dysregulation, including neurodegenerative and rare amyloid diseases. Its pipeline includes partnered clinical programs for Parkinson’s disease, ATTR amyloidosis, Alzheimer’s disease and other neurodegenerative diseases, as well as research and preclinical programs for conditions including ALS. Its candidates include prasinezumab, coramitug, BMS-986446 and PRX019. Prothena also develops CYTOPE®, a technology designed to target intracellular disease pathways, and has antibody, small molecule and vaccine approaches in its pipeline. Prothena makes money through collaborations and licenses with pharmaceutical companies, which can provide payments tied to development, regulatory and sales milestones, as well as royalties on product sales. Its partnerships include Roche, Novo Nordisk and Bristol Myers Squibb. Prothena is headquartered in Dublin, Ireland.

AlphAI earnings readThird Quarter 2026 · NOV 5Prothena Reports Third Quarter 2026 Financial Results and Business HighlightsVerdict: solid

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SCULLY WILLIAM P
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Insider Buying Signals: 3 Healthcare Stocks to Watch

Prothena (PRTA), Rapport (RAPP), and Azenta (AZTA) are on a watchlist due to insider buying and share repurchases. PRTA's 10% owner bought 27,000 shares at $9.47, with $272.2M cash and no debt. RAPP insiders bought $1.66M in shares, with $815.4M in cash post-financing. AZTA repurchased 2.3M shares, with $529M in cash. All await catalysts: PRTA's Alzheimer's trial data, RAPP's epilepsy study, and AZTA's fiscal 2027 outlook.

Prothena earnings missed by $0.11, revenue fell short of estimates

Prothena (PRTA) reported Q3 EPS of -$0.32, missing estimates by $0.11, with revenue of $620K, below the $9.59M consensus. The stock is down 9.93% over 3 months and 25.28% over 12 months. InvestingPro rates its financial health as 'good performance'.

PRTA sentiment & insider activity

Over the past 7 days, AlphAI's AI scored 2 news stories mentioning PRTA (PROTHENA CORP PUBLIC LTD CO). Coverage has skewed bearish: 0 bullish, 1 neutral, and 1 bearish.

Recent PRTA coverage spans earnings, insider activity and financial news.

In the last 30 days, PRTA insiders filed 5 SEC Form 4 transactions — 5 purchases ($3.3M) and no sales. The most active reporter was SCULLY WILLIAM P with 5 filings.

What's driving PRTA

AlphAI scores every news story that mentions PRTA with an AI model for sentiment and relevance, and aggregates insider trades from PROTHENA CORP PUBLIC LTD CO's SEC EDGAR Form 4 filings. Figures refresh continuously.

News on $PRTA

Score

Insider Buying Signals: 3 Healthcare Stocks to Watch

Prothena (PRTA), Rapport (RAPP), and Azenta (AZTA) are on a watchlist due to insider buying and share repurchases. PRTA's 10% owner bought 27,000 shares at $9.47, with $272.2M cash and no debt. RAPP insiders bought $1.66M in shares, with $815.4M in cash post-financing. AZTA repurchased 2.3M shares, with $529M in cash. All await catalysts: PRTA's Alzheimer's trial data, RAPP's epilepsy study, and AZTA's fiscal 2027 outlook.

Prothena: Q3 Earnings Snapshot

Prothena Corp. (PRTA) reported a Q3 loss of $16.5M, or 32 cents per share, beating analyst expectations of a 38 cents per share loss. The company generated $620K in revenue. According to Zacks Investment Research, the average estimate was for a larger loss.

Prothena Corporation plc: Prothena Reports Third Quarter 2026 Financial Results and Business Highlights

Prothena reported Q3 2026 net loss of $16.5M and 9M net loss of $2.4M, with $272.2M in cash. Coramitug showed reduced hsCRP in Phase 2 trial. Roche and Novo highlight prasinezumab and coramitug for Parkinson's and ATTR-CM. Phase 3 trials expected to complete in 2029. Prothena has $650M in upfront payments and potential $2.25B in milestones. Preclinical programs include TDP-43 CYTOPE and PRX012-TfR.

Prothena Reports Third Quarter 2026 Financial Results and Business Highlights

PROTHENA CORP PUBLIC LTD CO (PRTA) filed an SEC Form 8-K — Results of Operations and Financial Condition. Exhibit 99.1 PRESS RELEASE Prothena Reports Third Quarter 2026 Financial Results an d Business Highlights • Net cash used in operating and investing activities was $12.0 million in the third quarter and net cash used in operating and investing activities was $8.9 million for the

PROTHENA CORP PUBLIC LTD CO (PRTA): Termination of a Material Definitive Agreement

PROTHENA CORP PUBLIC LTD CO (PRTA) filed an SEC Form 8-K — Termination of a Material Definitive Agreement. Item 1.02 Termination of a Material Definitive Agreement. Following an internal strategic review, Bristol Myers Squibb informed Prothena Corporation plc (the “ Company ”) on October 28, 2026 that it has decided not to advance PRX019 further in the clinic. In May 2024, a subsidiar

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