$CLDI

Calidi Biotherapeutics, Inc. (NYSEAMERICAN:CLDI) Sees Significant Decline in Short Interest

Calidi Biotherapeutics (NYSEAMERICAN:CLDI) reported short interest fell to 670,614 shares as of May 15, down 77.9% from 3,038,967 on April 30, with 6.4% of shares sold short and a 0.3 days-to-cover ratio. The stock traded at $0.19, down 2.6%. The company reported EPS of -$0.43 for the quarter ended May 14, and institutional holders own 12.53%.

Original reporting
Published Jun 1, 2026, 5:15 AM UTC
Analysis
AlphAI AI DeskAI-generated
Added to AlphAI Jun 1, 2026, 5:37 AM UTC. Informational, not investment advice.
How this was made
AlphAI summarizes source reporting and applies a structured AI analysis for relevance, timing, sentiment and ticker impact. Always verify material claims with the original publisher.
Calidi Biotherapeutics, Inc. (NYSEAMERICAN:CLDI) Sees Significant Decline in Short Interest — source image
Decision brief

The 30-second read

$CLDINeutralMed
01

Why it matters

A large drop in short interest and a 0.3 days-to-cover ratio typically lowers the probability of a near-term short squeeze, shifting focus back to clinical/financing catalysts rather than positioning.

02

Market read

Traders may adjust tactical exposure based on reduced short pressure, but the article provides no new clinical outcome or guidance catalyst.

03

What to watch

The article doesn’t explain why shorts reduced exposure; with very low market cap and thin liquidity, price can still gap on small flows.

Relevance 7/10Novelty 7/10Timing: Positioning read-through for the next few sessions after the May short-interest print (as of May 15).

Background

The piece summarizes May short-interest levels for Calidi Biotherapeutics and notes recent institutional ownership changes plus the latest trading snapshot and last reported EPS.

Company-level read

Ticker impact

$CLDINeutralMedium confidence
Context

CLDI’s short interest fell 77.9% in May, with days-to-cover dropping to 0.3, signaling reduced short pressure.

Expected impact

Near-term bias slightly lower/neutral versus a short-squeeze setup; any move likely driven by liquidity and biotech risk rather than shorts.

Evidence & confidence

The article provides a large reduction in short interest and very low days-to-cover, which typically reduces the probability of a squeeze, but it does not tie the change to new fundamental catalysts.

Market effects

Limited direct sector impact; this is company-specific positioning data rather than a biotech-wide catalyst.

None indicated; US micro-cap liquidity dynamics dominate.

None indicated.

Counterpoint

Short interest can fall because shorts exit on liquidity/financing concerns rather than improved fundamentals, so price may not follow.

Key entities

  • Calidi Biotherapeutics, Inc.

    Clinical-stage biotech; subject of the short-interest decline and trading snapshot.

  • Institutional investors/hedge funds

    Reported to have modified holdings, with Geode Capital Management increasing and other funds initiating small stakes.

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