$ACXP

Acurx Pharmaceuticals, Inc.

Acurx Pharmaceuticals is a late-stage biopharmaceutical company developing small-molecule antibiotics for difficult-to-treat bacterial infections. Its candidates target Gram-positive bacteria by inhibiting DNA polymerase IIIC, an enzyme involved in bacterial DNA replication. The pipeline includes ibezapolstat, an oral antibiotic candidate for Clostridioides difficile infection, and ACX-375C, an early-stage candidate being developed for potential oral and parenteral treatment of infections including those caused by MRSA, VRE and drug-resistant Streptococcus pneumoniae. Acurx’s business focuses on research and development of antibiotic candidates. It acquired worldwide rights to manufacture, develop and commercialize ibezapolstat from GLSynthesis Inc. The company states that it may pursue late-stage development and commercialization through a pharmaceutical partner or conduct Phase 3 trials before partnering. Acurx Pharmaceuticals is headquartered in Staten Island, New York.

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Acurx Announces Publication in ASM Confirming Data on its DNA pol IIIC Inhibitor Pipeline of Antibiotics Demonstrating a Potential Microbiome-Sparing Class Effect

Acurx Pharmaceuticals (NASDAQ: ACXP) announced the publication of a study in ASM Microbiology Spectrum showing its DNA pol IIIC inhibitors preserved gut microbiome diversity and function in a murine model, unlike linezolid. The company's preclinical compounds target MRSA and other Gram-positive infections, with FDA QIDP and Fast-Track designations. Acurx is also advancing ibezapolstat for C. difficile infection into Phase 3 trials.

Acurx Pharmaceuticals, Inc. (ACXP): Submission of Matters to a Vote of Security Holders

Acurx Pharmaceuticals, Inc. (ACXP) filed an SEC Form 8-K — Submission of Matters to a Vote of Security Holders. Item 5.07 Submission of Matters to a Vote of Security Holders. At the close of business on August 20, 2026, the record date of the Annual Meeting of Stockholders of Acurx Pharmaceuticals, Inc. (the “Company”) held on October 16, 2026 (the “Annual Meeting”), there were 5,471,297 s

Top Biotech Gainers: FDMT, OABI, ACXP Rally On Pipeline And Regulatory News

Biotech gainers were led by 4D Molecular Therapeutics (FDMT), up over 12%, after Phase 3 enrollment progress for 4D-150 in wet AMD and other pipeline updates, plus a $200M credit facility. OmniAb (OABI) rose over 11% on an Eli Lilly collaboration and higher 2026 cash guidance. Acurx (ACXP) gained over 14% after FDA conditional acceptance of CIFBEZY as ibezapolstat’s brand name.

ACXP sentiment & insider activity

Recent ACXP coverage spans financial news, technology and corporate actions.

What's driving ACXP

  • Positive preclinical results may lift investor sentiment and support a near‑term price rally.

    prnewswire.com · Oct 21, 2026

  • The filing confirms quorum and election outcomes but provides no new financial guidance or material corporate change.

    SEC EDGAR 8-K · Oct 16, 2026

  • Regulatory and trademark milestones reduce commercialization friction and support progression toward an international Phase 3 registration program.

    rttnews.com · Aug 17, 2026

  • Near-term trading focus is funding runway plus FDA engagement and incremental regulatory/IP progress for ibezapolstat, with dilution risk from the April financing.

    prnewswire.com · Aug 14, 2026

  • The stock experienced significant volatility due to a 1-for-20 reverse split and ongoing development of antibiotics. The news indicates potential for increased volatility but also highlights the company's developmental stage and limited earnings.

    AD HOC NEWS · May 15, 2026

AlphAI scores every news story that mentions ACXP with an AI model for sentiment and relevance, and aggregates insider trades from Acurx Pharmaceuticals, Inc.'s SEC EDGAR Form 4 filings. Figures refresh continuously.

News on $ACXP

Score
$ACXPMedAI 8/10

Acurx Announces Publication in ASM Confirming Data on its DNA pol IIIC Inhibitor Pipeline of Antibiotics Demonstrating a Potential Microbiome-Sparing Class Effect

Acurx Pharmaceuticals (NASDAQ: ACXP) announced the publication of a study in ASM Microbiology Spectrum showing its DNA pol IIIC inhibitors preserved gut microbiome diversity and function in a murine model, unlike linezolid. The company's preclinical compounds target MRSA and other Gram-positive infections, with FDA QIDP and Fast-Track designations. Acurx is also advancing ibezapolstat for C. difficile infection into Phase 3 trials.

Acurx Pharmaceuticals, Inc. (ACXP): Submission of Matters to a Vote of Security Holders

Acurx Pharmaceuticals, Inc. (ACXP) filed an SEC Form 8-K — Submission of Matters to a Vote of Security Holders. Item 5.07 Submission of Matters to a Vote of Security Holders. At the close of business on August 20, 2026, the record date of the Annual Meeting of Stockholders of Acurx Pharmaceuticals, Inc. (the “Company”) held on October 16, 2026 (the “Annual Meeting”), there were 5,471,297 s

Acurx Pharmaceuticals stock (US00366D1037): reverse split and price swings keep biotech in focus

Acurx Pharmaceuticals (ACXP) has experienced significant price volatility, including a 1-for-20 reverse stock split in August 2025, as it continues to develop antibiotic candidates for difficult infections. The company, a clinical-stage biopharmaceutical firm, focuses on novel antibiotics, with its lead candidate targeting Clostridioides difficile infection (CDI). As a development-stage company, its valuation is primarily driven by clinical milestones, regulatory progress, and financing activities rather than current earnings.

Acurx Pharmaceuticals, Inc. Reports First Quarter 2026 results and Provides Business Update

Acurx Pharmaceuticals (ACXP) reported a Q1 2026 net loss of $1.7 million, narrowing from $2.1 million, with cash increasing to $9.3 million. The company is advancing its ibezapolstat program for C. difficile, initiating a Phase 2 trial for recurrent CDI and strengthening its patent portfolio. Despite operational progress, the stock experienced a mild negative market reaction, continuing a historical pattern of post-earnings declines.

Acurx Pharmaceuticals raises $2.5M in direct offering

Acurx Pharmaceuticals (NASDAQ:ACXP) announced a direct offering of 825,085 shares of common stock at $3.03 per share, aiming to raise approximately $2.5 million before expenses. Concurrently, it will issue unregistered short-term warrants that could generate an additional $4.6 million if fully exercised. The company plans to use the net proceeds for working capital and general corporate purposes, with analysts maintaining optimistic price targets.

Antibiotic developer Acurx sets March 13 call on 2025 results, business update

Acurx Pharmaceuticals (NASDAQ: ACXP) will report its full year and fourth quarter 2025 financial results on Friday, March 13, 2026, at 8:00 a.m. ET, before U.S. markets open. Management, including CEO David P. Luci and CFO Robert G. Shawah, will host a conference call to discuss the results and provide a business update. The company's lead antibiotic candidate, Ibezapolstat, is preparing for international Phase 3 clinical trials for C. difficile Infection (CDI) and has received positive regulatory guidance from both the EMA and FDA.

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