$ATNM

Actinium Pharmaceuticals, Inc.

Actinium Pharmaceuticals, headquartered in New York, NY, is a clinical-stage biopharmaceutical company developing targeted radiotherapies for patients with solid tumors and hematologic malignancies. Its pipeline includes ATNM-400, an Ac-225 antibody radioconjugate targeting a non-PSMA antigen in solid tumors, and Actimab-A, a CD33-targeted Ac-225 therapy being developed for AML and MDS and for use with checkpoint inhibitors in solid tumors. Actinium also develops Iomab-B, a CD45-targeted conditioning therapy for bone marrow transplant, and Iomab-ACT, a CD45-targeted conditioning platform for cell and gene therapies. Actinium’s business is centered on developing these product candidates for clinical use. It conducts development programs independently and with partners, including the National Cancer Institute under a Cooperative Research and Development Agreement, and seeks strategic partnerships to advance its hematology programs. The company is establishing a radiopharmaceutical manufacturing facility and has an end-to-end supply chain spanning isotope sourcing, drug product production and delivery to treatment sites.

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Actinium Pharmaceuticals Announces Enrollment in the RADIANZ Imaging Clinical Trial Intended to Demonstrate the Pan-Cancer Potential of ATNM-400, A First-in-Class HER3-Targeting Radiotherapy

Actinium Pharmaceuticals (ATNM) has begun enrolling patients in the RADIANZ clinical trial for ATNM-400, a HER3-targeting radiotherapy. The study aims to expand ATNM-400's potential beyond prostate cancer to other solid tumors. Initial data in prostate cancer showed tumor uptake and no dose-limiting toxicities. The company plans to present additional breast cancer data at the San Antonio Breast Cancer Symposium.

Actinium Pharmaceuticals Announces Three ASH 2026 Abstracts Highlighting Iomab-ACT Clinical Results in CAR T-Cell Therapy and Sickle Cell Disease

Actinium Pharmaceuticals (ATNM) announced three abstracts for ASH 2026, highlighting Iomab-ACT's potential in CAR T-cell therapy and sickle cell disease. The studies explore Iomab-ACT as a conditioning agent before cellular therapies, reducing reliance on chemotherapy. According to the company, the results support Iomab-ACT's development as a universal targeted conditioning regimen.

Actinium Pharmaceuticals Announces ASH 2026 Abstract Highlighting Long-Term Results of Actimab-A in Combination with CLAG-M in Relapsed or Refractory AML

Actinium Pharmaceuticals (ATNM) announced long-term safety results of Actimab-A combined with CLAG-M for relapsed/refractory AML at ASH 2026. The study showed potential for bone marrow recovery and addressed kidney/liver toxicities. Prior data showed 1- and 2-year survival rates of 59% and 32% in venetoclax-failed patients, and 51% and 19% in TP53-mutated AML patients. Actinium aims to develop Actimab-A as a mutation-agnostic AML treatment.

ATNM sentiment & insider activity

Over the past 7 days, AlphAI's AI scored 2 news stories mentioning ATNM (Actinium Pharmaceuticals, Inc.). Coverage has skewed bullish: 1 bullish, 1 neutral, and 0 bearish.

Recent ATNM coverage spans financial news, technology and corporate actions.

What's driving ATNM

AlphAI scores every news story that mentions ATNM with an AI model for sentiment and relevance, and aggregates insider trades from Actinium Pharmaceuticals, Inc.'s SEC EDGAR Form 4 filings. Figures refresh continuously.

News on $ATNM

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$ATNMMedClinical / regulatory· trial start

Actinium Pharmaceuticals Announces Enrollment in the RADIANZ Imaging Clinical Trial Intended to Demonstrate the Pan-Cancer Potential of ATNM-400, A First-in-Class HER3-Targeting Radiotherapy

Actinium Pharmaceuticals (ATNM) has begun enrolling patients in the RADIANZ clinical trial for ATNM-400, a HER3-targeting radiotherapy. The study aims to expand ATNM-400's potential beyond prostate cancer to other solid tumors. Initial data in prostate cancer showed tumor uptake and no dose-limiting toxicities. The company plans to present additional breast cancer data at the San Antonio Breast Cancer Symposium.

$ATNMMedAI 8/10

Actinium Pharmaceuticals Announces Three ASH 2026 Abstracts Highlighting Iomab-ACT Clinical Results in CAR T-Cell Therapy and Sickle Cell Disease

Actinium Pharmaceuticals (ATNM) announced three abstracts for ASH 2026, highlighting Iomab-ACT's potential in CAR T-cell therapy and sickle cell disease. The studies explore Iomab-ACT as a conditioning agent before cellular therapies, reducing reliance on chemotherapy. According to the company, the results support Iomab-ACT's development as a universal targeted conditioning regimen.

$ATNMMedAI 8/10Clinical / regulatory· topline data

Actinium Pharmaceuticals Announces ASH 2026 Abstract Highlighting Long-Term Results of Actimab-A in Combination with CLAG-M in Relapsed or Refractory AML

Actinium Pharmaceuticals (ATNM) announced long-term safety results of Actimab-A combined with CLAG-M for relapsed/refractory AML at ASH 2026. The study showed potential for bone marrow recovery and addressed kidney/liver toxicities. Prior data showed 1- and 2-year survival rates of 59% and 32% in venetoclax-failed patients, and 51% and 19% in TP53-mutated AML patients. Actinium aims to develop Actimab-A as a mutation-agnostic AML treatment.

Actinium Pharmaceuticals Announces Acceptance of ATNM-400 Abstract for Presentation at SABCS 2026 Highlighting Activity Across Therapy-Resistant Breast Cancer Models

Actinium Pharmaceuticals (ATNM) announced that its abstract on ATNM-400, a targeted alpha therapy for breast cancer, was accepted for presentation at the 2026 San Antonio Breast Cancer Symposium. The study highlights ATNM-400's efficacy across therapy-resistant breast cancer subtypes, reinforcing its potential as a pan-tumor treatment. The company is also developing ATNM-400 for prostate, lung, colorectal, and ovarian cancers.

After a cancer drug failed, Actinium's experimental treatment inhibited ovarian tumor growth by 50% in a model.

Actinium Pharmaceuticals (ATNM) reported that its experimental treatment, ATNM-400, showed significant tumor growth inhibition in lung, colorectal, and ovarian cancer models. The drug demonstrated activity across various cancer types, including treatment-resistant cases, supporting its potential as a pan-tumor therapy. The company plans to advance ATNM-400 across multiple solid tumor indications, with ongoing clinical development in prostate cancer.

$ATNMMedAI 8/10

Lab tests show an experimental treatment active in lung, bowel and ovarian cancer models, including resistant tumors.

Actinium Pharmaceuticals presented preclinical data showing ATNM-400, its targeted radiotherapy, demonstrated antitumor activity in lung, colorectal, and ovarian cancer models, including resistant tumors. The findings support ATNM-400's potential as a monotherapy and in combination with existing treatments across multiple cancer indications.

$ATNMLowExec change· appointed

Actinium Pharmaceuticals, Inc. (ATNM): Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers

Actinium Pharmaceuticals, Inc. (ATNM) filed an SEC Form 8-K — Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers. Exhibit 99.1 Actinium Pharmaceuticals Strengthens Leadership Team with Appointment of Matt David, M.D. as Chief Financial Officer NEW YORK, October 15, 2026 /PRNewswire/ -- Actinium Pharmaceuticals, Inc. (NYSE American: ATNM) (“Actinium” or the “Company”), a pioneer in the develo

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