$SEPN

Septerna, Inc.

AlphAI earnings readSecond Quarter 2026 · AUG 10Septerna Highlights Business Progress and Reports Second Quarter 2026 Financial ResultsVerdict: solid

Reads like this one publish minutes after the filing lands on EDGAR. Get them as JSON over the API or inside your AI agent over MCP.

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$126K
Long Daniel D.
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See all $SEPN insider activity →
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Septerna (SEPN) awards CMO 275,000 options at $37.37

Septerna (SEPN) disclosed that its CMO, Rajiv Patni, received 275,000 stock options on September 8, 2026, with an exercise price of $37.37 per share. The options expire on September 7, 2036, with 25% vesting on August 24, 2027, and the remainder in monthly installments over three years, contingent on his continued service.

Septerna Announces Inducement Grant Under Nasdaq Listing Rule

Septerna, a biotech company, granted stock awards to new employees under Nasdaq's Rule 5635(c)(4). The awards are part of an inducement plan to attract talent. According to the company, the grants are intended to align employees' interests with shareholders' long-term success.

SEPN sentiment & insider activity

Over the past 7 days, AlphAI's AI scored 2 news stories mentioning SEPN (Septerna, Inc.). Coverage has been balanced: 0 bullish, 2 neutral, and 0 bearish.

Recent SEPN coverage spans financial news, insider activity and corporate actions.

In the last 30 days, SEPN insiders filed 1 SEC Form 4 transaction — no purchases and 1 sale ($126K). The most active reporter was Long Daniel D., SVP, Drug Discovery, with 1 filing. 100% of those filings were made under pre-arranged Rule 10b5-1 plans.

What's driving SEPN

  • Small insider option grant with modest potential dilution; limited immediate price impact.

    stocktitan.net · Sep 10, 2026

  • Septerna, a biotech company, granted stock awards to new employees under Nasdaq's Rule 5635(c)(4). The awards are part of an inducement plan to attract talent. According to the company, the grants are intended to align employees' interests with shareholders' long-term success.

    tradingview.com · Sep 10, 2026

  • No immediate price impact expected as the filing reports zero holdings.

    stocktitan.net · Sep 3, 2026

  • The hire may modestly improve Septerna's regulatory and clinical execution, supporting near‑term trial milestones.

    simplywall.st · Aug 25, 2026

  • The new CMO brings extensive drug development experience, potentially accelerating Septerna's GPCR pipeline.

    rttnews.com · Aug 25, 2026

AlphAI scores every news story that mentions SEPN with an AI model for sentiment and relevance, and aggregates insider trades from Septerna, Inc.'s SEC EDGAR Form 4 filings. Figures refresh continuously.

News on $SEPN

Score

Septerna (SEPN) awards CMO 275,000 options at $37.37

Septerna (SEPN) disclosed that its CMO, Rajiv Patni, received 275,000 stock options on September 8, 2026, with an exercise price of $37.37 per share. The options expire on September 7, 2036, with 25% vesting on August 24, 2027, and the remainder in monthly installments over three years, contingent on his continued service.

$SEPNLow

Is Septerna (SEPN) Elevating Its Clinical Strategy With a Veteran Regulatory Leader at the Helm?

Septerna (SEPN) appointed Rajiv Patni, M.D., as Chief Medical Officer, bringing 25+ years of biopharmaceutical experience. Investors may view this as positive for advancing its pipeline and meeting clinical milestones, despite current losses. The company's valuation is tied to its GPCR-focused platform and early clinical assets, with key catalysts being SEP-631 and SEP-479 trials, and a Novo Nordisk collaboration. Dr. Patni's regulatory expertise could improve trial and regulatory execution, but

$SEPNMed

Septerna Appoints Rajiv Patni, M.D., As Chief Medical Officer

Septerna Inc. (SEPN) appointed Rajiv Patni, M.D., as Chief Medical Officer. Dr. Patni has over 20 years of experience in clinical development and regulatory affairs. The company aims to advance its GPCR-targeted medicines into clinical trials. SEPN's stock closed at $40.52, up 1.30%, and is currently trading at $40.44 in pre-market.

$PALLow

Top insider buys and sells disclosed on Friday

Investing.com reported major US insider trades disclosed Friday. Buys: PAL director Rohit Lal bought $272.5k; OTLK director/10% owner Ghiath Sukhtian bought about 2.5M shares and warrants for ~$2.5M; CLPR director Sam Levinson bought ~$488.8k; OPFI CEO Todd Schwartz bought ~$144k; OPEN CEO Kasra Nejatian bought ~$100k. Sells: CRWV 10% owner Magnetar sold ~$231.6M then ~$213.8M; ANET CEO Ullal trust sales ~$119.3M; SEPN RA Capital sold $63.45M; KRYS director Rossi sold ~$8.23M.

$SEPNLow

Third Rock Ventures V, L.P. sold $7.4M of SEPN

Third Rock Ventures V, L.P. sold 147,200 shares of Septerna, Inc. (SEPN) at an average of $50.27 ($50.27–$51.08, $7.40M total) across 2 trades on 2026-08-12 under a Rule 10b5-1 trading plan. Filed jointly with Third Rock Ventures GP V, LP (10% owner), TRV GP V, LLC (10% owner), Third Rock Ventures VI, L.P. (10% owner), Third Rock Ventures GP VI, L.P. (10% owner) and TRV GP VI, LLC (10% owner).

$SEPNMed

Septerna, Inc. (SEPN): Results of Operations and Financial Condition

Septerna, Inc. (SEPN) filed an SEC Form 8-K — Results of Operations and Financial Condition. Exhibit 99.1 Septerna Highlights Business Progress and Reports Second Quarter 2026 Financial Results Phase 1 Clinical Trial Ongoing for SEP-479, an Oral Small Molecule PTH1R Agonist SEP-479 Observed Clinical Pharmacokinetic Profile Supports Once-Daily Dosing; SAD / MAD Data Expec

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