$CVKD

Cadrenal Therapeutics, Inc.

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1
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$7K
Pham Quang X
100%
Med

Pham Quang X sold $7K of CVKD

Pham Quang X (CEO and Chairman) sold 1,165 shares of Cadrenal Therapeutics, Inc. (CVKD) at $5.69 on 2026-05-22 under a Rule 10b5-1 trading plan.

CVKD: CAD-1005 moves to phase III for HIT, aiming to address a critical unmet need with strong safety data

Cadrenal Therapeutics, Inc.'s CAD-1005, a novel IV therapy for Heparin-Induced Thrombocytopenia (HIT), is progressing to phase III trials following promising phase II results and strong safety data. The drug addresses a significant unmet medical need, has Orphan Drug and Fast Track designations, and may have potential broader applications in diabetes and obesity. This advancement is based on information from a recent virtual investor forum.

HIT trial: CAD-1005 patients had 50% clot rate vs >75% on placebo

Cadrenal Therapeutics reported encouraging Phase 2 results for CAD-1005 in heparin-induced thrombocytopenia (HIT), showing a greater than 25% absolute reduction in thrombotic events compared to placebo. While the drug did not improve platelet count recovery, patients receiving CAD-1005 experienced fewer thrombotic events (50%) compared to the placebo group (>75%). An End-of-Phase 2 FDA meeting is scheduled for March 2026 to discuss the path forward for a Phase 3 study.