$OBIO

Orchestra BioMed Holdings, Inc.

2
0
0
$59K
$74K
Sherman Darren
33%
See all $OBIO insider activity →

Biotech Stocks At 52-Week Highs - AMLX +63% With Phase 3 Data, VOGX +25%, OBIO +19%, ATRC, CRL

Several biotech stocks hit 52-week highs on August 18, 2026. Amylyx (AMLX) surged 63% to $35.39 after positive Phase 3 data and a $350M share offering. Vogenx (VOGX) rose 25% to $20.01 post-IPO. AtriCure (ATRC) reached $46.33 with 12.8% revenue growth. Charles River (CRL) hit $289.60 despite a 2.7% revenue dip. Orchestra BioMed (OBIO) climbed 19% to $5.77 with FDA breakthrough designations.

OBIO sentiment & insider activity

Over the past 7 days, AlphAI's AI scored 2 news stories mentioning OBIO (Orchestra BioMed Holdings, Inc.). Coverage has skewed bullish: 2 bullish, 0 neutral, and 0 bearish.

Recent OBIO coverage spans financial news, insider activity and market movers.

In the last 30 days, OBIO insiders filed 3 SEC Form 4 transactions — 2 purchases ($59K) and 1 sale ($74K). The most active reporter was Sherman Darren, See Remarks, with 2 filings. 33% of those filings were made under pre-arranged Rule 10b5-1 plans.

What's driving OBIO

AlphAI scores every news story that mentions OBIO with an AI model for sentiment and relevance, and aggregates insider trades from Orchestra BioMed Holdings, Inc.'s SEC EDGAR Form 4 filings. Figures refresh continuously.

News on $OBIO

Score
$AMLXHighAI 8/10

Biotech Stocks At 52-Week Highs - AMLX +63% With Phase 3 Data, VOGX +25%, OBIO +19%, ATRC, CRL

Several biotech stocks hit 52-week highs on August 18, 2026. Amylyx (AMLX) surged 63% to $35.39 after positive Phase 3 data and a $350M share offering. Vogenx (VOGX) rose 25% to $20.01 post-IPO. AtriCure (ATRC) reached $46.33 with 12.8% revenue growth. Charles River (CRL) hit $289.60 despite a 2.7% revenue dip. Orchestra BioMed (OBIO) climbed 19% to $5.77 with FDA breakthrough designations.

$AMLXMed

Biotech Stocks Rally: AMLX, RCEL, CNSP Gain On Key Clinical And Corporate News

Amylyx Pharmaceuticals (AMLX) rose 55.71% after positive Phase 3 LUCIDITY trial results for Avexitide. AVITA Medical (RCEL) gained 21.90% on cost-effective PermeaDerm-I study data. CNS Pharmaceuticals (CNSP) increased 12.04% following a strategic financing and pipeline pivot. Orchestra BioMed (OBIO) advanced 15.04% with strategic capital and hypertension program progress. NeOnc Technologies (NTHI) climbed 13.80% on encouraging Phase 2a NEO100 data.

$OBIOLow

Orchestra BioMed Holdings, Inc. (OBIO): Submission of Matters to a Vote of Security Holders

Orchestra BioMed Holdings, Inc. (OBIO) filed an SEC Form 8-K — Submission of Matters to a Vote of Security Holders. false 0001814114 0001814114 2026-06-23 2026-06-23 iso4217:USD xbrli:shares iso4217:USD xbrli:shares UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Repor

$OBIOLow

RTW funds exercise 1.25M Orchestra BioMed (NASDAQ: OBIO) pre-funded warrants

RTW funds have exercised 1,250,032 pre-funded warrants of Orchestra BioMed (NASDAQ: OBIO) at $0.0001 per share on a cashless basis. This transaction resulted in the issuance of 1,250,000 shares to RTW, with 32 shares withheld to cover the exercise price. Following the exercise, the RTW funds indirectly hold 9,556,095 shares of common stock and 2,386,331 pre-funded warrants, while adhering to a beneficial ownership cap of 19.99%.

$OBIOMed

Orchestra BioMed (OBIO) stake rises to 19.2% after RTW warrant exercise

RTW Investments and affiliated funds have increased their beneficial ownership in Orchestra BioMed Holdings to 19.2% after exercising pre-funded warrants. On April 27, 2026, RTW funds exercised pre-funded warrants for 1,250,032 shares on a cashless basis, resulting in 1,250,000 new common shares for Orchestra BioMed. This transaction, combined with additional exercisable warrants, means RTW Investments and Dr. Roderick Wong beneficially own 11,942,394 shares.

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