$QNRX

Quoin Pharmaceuticals Ltd.

Quoin Pharmaceuticals develops therapeutic drug candidates for rare and orphan diseases, particularly conditions with no approved or limited treatments. Its lead candidate, QRX003, is a topical lotion being studied for Netherton Syndrome and Peeling Skin Syndrome. The company also has QRX008, a potential treatment for scleroderma, and QRX009, a program developing topical rapamycin formulations for rare diseases. Quoin has research agreements with Queensland University of Technology and University College Cork, and commercial partnerships for QRX003 covering 61 countries outside its core territories. Quoin has not commercialized products or generated revenue. It plans to commercialize approved products directly in the U.S., Europe and Japan, and use partners in other markets. Its business includes developing product candidates and pursuing licensing, research partnerships and other transactions to expand its pipeline. Quoin’s headquarters are in Ashburn, Virginia.

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Quoin Pharmaceuticals Announces Publication of Peer-Reviewed Paper on QRX003 for Netherton Syndrome in Dermatology and Therapy

Quoin Pharmaceuticals Ltd. (QNRX) filed an SEC Form 8-K — Other Events. Exhibit 99.1 Quoin Pharmaceuticals Announces Publication of Peer-Reviewed Paper on QRX003 for Netherton Syndrome in Dermatology and Therapy – Peer-Reviewed Paper Introducing QRX003 and Its Mechanism of Action in Netherton Syndrome Now Published – Case Report Details 21 Months of

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$QNRXMedAI 8/10

Quoin Pharmaceuticals Announces Publication of Peer-Reviewed Paper on QRX003 for Netherton Syndrome in Dermatology and Therapy

Quoin Pharmaceuticals Ltd. (QNRX) filed an SEC Form 8-K — Other Events. Exhibit 99.1 Quoin Pharmaceuticals Announces Publication of Peer-Reviewed Paper on QRX003 for Netherton Syndrome in Dermatology and Therapy – Peer-Reviewed Paper Introducing QRX003 and Its Mechanism of Action in Netherton Syndrome Now Published – Case Report Details 21 Months of

$QNRXMedAI 8/10

Canaccord initiates Quoin Pharmaceuticals stock at buy on rare skin disease drug potential

Canaccord Genuity initiated coverage on Quoin Pharmaceuticals (QNRX) with a buy rating and $18 price target, citing its lead drug QRX003 for Netherton syndrome. The stock is down 74% over a year. Phase 2/3 study met primary endpoint, with topline data expected in 2027. Canaccord projects 2028 launch and $300M peak sales. BTIG also initiated coverage with a buy rating and $14 target.

$QNRXMedAI 8/10

Quoin Pharmaceuticals Announces European Medicines Agency (EMA) Grants Orphan Drug Designation for QRX003 for the Treatment of Peeling Skin Syndrome

Quoin Pharmaceuticals Ltd. (QNRX) filed an SEC Form 8-K — Other Events. Exhibit 99.1 Quoin Pharmaceuticals Announces European Medicines Agency (EMA) Grants Orphan Drug Designation for QRX003 for the Treatment of Peeling Skin Syndrome – Company on track to initiate first-ever formal clinical trial in Peeling Skin Syndrome before year end – Orphan Drug

$QNRXMedAI 8/10

Europe gives a rare skin disease drug special status. Approval could bring 10 years' exclusivity.

Quoin Pharmaceuticals (QNRX) announced that its lead product QRX003 received Orphan Drug Designation in Europe for treating Peeling Skin Syndrome. This designation provides 10 years of market exclusivity upon approval and includes benefits like fee reductions and access to EU grants. The company plans to initiate the first formal clinical trial for Peeling Skin Syndrome by year-end. QRX003 has also received multiple regulatory designations for Netherton Syndrome in the US, Europe, and Japan.

Quoin Pharmaceuticals Announces Acceptance of QRX003 Paper in Dermatology and Therapy

Quoin Pharmaceuticals (QNRX) announced a peer-reviewed paper on QRX003, its investigational treatment for Netherton Syndrome, was accepted by Dermatology and Therapy. The paper details QRX003's mechanism and a case report of a pediatric patient's positive response. Quoin also reported interim Phase 2/3 study results, with 66.7% of participants achieving the primary endpoint. QRX003 has received Orphan Drug and Fast Track designations.

Four Small-Cap Stocks Report New Developments (CHGA, QNRX, MYSE, LNKS)

Change Agents Corp. (CHGA) launched a subsidiary for AI-enabled counter-drone tech and added a retired general to its advisory board. Quoin Pharmaceuticals (QNRX) reported positive Phase 2/3 trial data for QRX003 and raised $50M. Myseum.AI (MYSE) partnered with Fujifilm for print-on-demand products. Linkers Industries (LNKS) increased its stake in LPW Electronics, boosting its Thai operations.

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